Investigating the histopathological effects of saffron petal (Crocus Sativus L.) hydroalcoholic extract on kidney and liver functional parameters in rats

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Effects of saffron (Crocus sativus) petal ethanolic extract on hematology, antibody response, and spleen histology in rats

OBJECTIVE Saffron petal is a by-product that contains flavonoids and anthocyanins. In order to study the effects of saffron petal extract (SPE) on blood parameters, immune system, and spleen histology, five treatments (n=6) were used in a completely randomized design. MATERIALS AND METHODS The treatments were 0, 75, 150, 225, and 450 mg/kg body weight of SPE. The SPE was injected intraperiton...

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Effects of saffron (Crocus sativus) petal ethanolic extract on hematology, antibody response, and spleen histology in rats

Objective: Saffron petal is a by-product that contains flavonoids and anthocyanins. In order to study the effects of saffron petal extract (SPE) on blood parameters, immune system, and spleen histology, five treatments (n=6) were used in a completely randomized design. Materials and Methods: The treatments were 0, 75, 150, 225, and 450 mg/kg body weight of SPE. The SPE was injected intraperiton...

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Protective effect of Crocus sativus L. (Saffron) extract on spinal cord ischemia-reperfusion injury in rats

OBJECTIVES Ischemia/reperfusion (I/R) injury of spinal cord is leading to the paraplegia observed. In this study, we investigated the protective effect of the saffron extract on spinal cord I/R injury. MATERIALS AND METHODS Thirty five male Sprague-Dawley rats were divided into 5 groups: intact, sham surgery, normal saline (NS), low dose saffron aqua extract, high dose saffron aqua extract. ...

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Hydroalcoholic extract of Crocus sativus effects on bronchial inflammatory cells in ovalbumin sensitized rats

OBJECTIVE Inflammation is one of the major components of asthma. Our aim was to evaluate the effects of C. sativus extract on total and differential white blood cells (WBC) count in lung lavage fluid (LLF) of ovalbumin-sensitized rats. MATERIALS AND METHODS Forty rats were divided into five groups (n = 8 for each group) as control (C), sensitized with injection and inhalation of ovalbumin (OA...

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Antitumor Effect of Saffron (Crocus sativus L.): Overview and Perspectives

From ancient times, saffron dried stigmas of Crocus sativus L. is widely used as a drug against different human diseases. In the beginning of 1990 ́s scientific literature reported for the first time the antitumor activity of saffron. During the last decade different laboratories of the world (including ours) have accumulated sufficient scientific evidence to suggest that saffron, and its main i...

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ژورنال

عنوان ژورنال: Biomedical Research and Therapy

سال: 2020

ISSN: 2198-4093,2198-4093

DOI: 10.15419/bmrat.v7i4.600